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Polyketide sugar unit biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
dTDP-6-deoxy-beta-L-talose + NAD+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADH + H+ 1.1.1.339 dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)
1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]


dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2-oxoglutarate <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + L-glutamate 2.6.1.106 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase

S-adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose <=> S-adenosyl-L-homocysteine + dTDP-alpha-D-forosamine + H+ 2.1.1.324 dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase

dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose 5.1.3

S-adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose + H+ 2.1.1

S-adenosyl-L-methionine + dTDP-4-dehydro-6-deoxy-alpha-D-gulose <=> S-adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose 2.1.1

dTDP-glucose <=> H2O + dTDP-4-dehydro-6-deoxy-D-glucose 4.2.1.46 dTDP-glucose 4,6-dehydratase
4.2.1.76 UDP-glucose 4,6-dehydratase


dTDP-4-oxo-5-C-methyl-L-rhamnose <=> dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose not assigned

dTDP-L-noviose + NAD+ <=> dTDP-4-oxo-5-C-methyl-L-rhamnose + NADH + H+ 1.1.1

dTDP-D-glucuronate + NAD+ <=> dTDP-4-oxo-alpha-D-xylose + CO2 + NADH + H+ 1.1.1

S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose <=> S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-glucopyranose + H+ 2.1.1.235 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

dTTP + alpha-D-glucose_1-phosphate + H+ <=> dTDP-glucose + diphosphate 2.7.7.24 glucose-1-phosphate thymidylyltransferase
2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase
2.7.7.9 UTP---glucose-1-phosphate uridylyltransferase



dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose 5.1.3

dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ <=> dTDP-L-rhamnose + NADP+ 1.1.1
1.1.1.133 dTDP-4-dehydrorhamnose reductase


dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O 4.2.1.159 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase

dTDP-3-methyl-4-oxo-alpha-D-ribopyranose <=> dTDP-madurosamine not assigned

acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H+ 2.3.1.197 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase

dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose <=> dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose 5.1.3

dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ <=> dTDP-4-oxo-2,6-dideoxy-D-allose + NADP+ 1.1.1

dTDP-6-deoxy-alpha-D-allose + NADP+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADPH + H+ 1.1.1.364 dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

dTDP-3-dehydro-2,6-dideoxy-alpha-D-glucose <=> TDP-3-amino-2,3,6-trideoxy-alpha-D-glucose not assigned

dTDP-alpha-D-fucopyranose + NADP+ <=> dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase
1.1.1.B28


S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose + H+ 2.1.1.236 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase

dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate 2.6.1.89 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase

S-adenosyl-L-methionine + dTDP-L-rhamnose <=> S-adenosyl-L-homocysteine + dTDP-3-O-methyl-beta-L-rhamnose 2.1.1

S-adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-L-mannose <=> S-adenosyl-L-homocysteine + dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose 2.1.1

dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose 5.3.2.4 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming)

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-glutamate 2.6.1.90 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase

dTDP-4-oxo-alpha-D-xylose <=> dTDP-3-methyl-4-oxo-alpha-D-ribopyranose 2.1.1

dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + reduced_ferredoxin + O2 <=> dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + oxidized_ferredoxin + H2O 1.14.15

TDP-3-amino-2,3,6-trideoxy-alpha-D-glucose <=> dTDP-D-angolosamine not assigned

dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ 1.1.1.133 dTDP-4-dehydrorhamnose reductase

dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + NADPH + H+ <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + NADP+ 1.1.1

dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-4-dehydro-beta-L-rhamnose 5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase

dTDP-6-deoxy-alpha-D-allose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADH + H+ 1.1.1.364 dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-L-allose <=> dTDP-L-megosamine not assigned

S-adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + H+ 2.1.1.234 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase
2.1.1.235 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase


dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-deoxy-4-thio-alpha-D-digitoxose not assigned

dTDP-alpha-D-fucopyranose <=> dTDP-alpha-D-fucofuranose 5.4.99.59 dTDP-fucopyranose mutase

dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose 5.3.2.3 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)

dTDP-glucose + 2 NAD+ + H2O <=> dTDP-D-glucuronate + 2 NADH + 2 H+ 1.1.1

dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + 2-oxoglutarate <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + L-glutamate 2.6.1

dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose <=> dTDP-3-dehydro-2,6-dideoxy-alpha-D-glucose not assigned

S-adenosyl-L-methionine + dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-2,3,6-trideoxy-4-keto-D-glucose + H+ 2.1.1

2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose <=> L-glutamate + dTDP-4-dehydro-6-deoxy-D-glucose 2.6.1.33 dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
2.6.1.B6


dTDP-4-amino-4,6-dideoxy-5-C-methyl-D-allose <=> dTDP-4-dimethylamino-4,6-dideoxy-5-C-methyl-D-allose 2.1.1

dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + 2-oxoglutarate <=> dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + L-glutamate 2.6.1.110 dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase

dTDP-4-amino-2,4-dideoxy-beta-L-xylose + 2-oxoglutarate <=> dTDP-4-oxo-2-deoxy-beta-L-xylose + L-glutamate 2.6.1

dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose 5.1.3.27 dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase

dTDP-L-olivose + NADP+ <=> dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ 1.1.1

dTDP-4-oxo-alpha-D-xylose <=> dTDP-4-oxo-2-deoxy-alpha-D-pentos-2-ene + H2O 4.2.1

S-adenosyl-L-methionine + dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + reduced_acceptor <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + NH3 + L-methionine + 5''-deoxyadenosine + acceptor + H+ 4.3.1.30 dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase

dTDP-beta-L-mycarose + NADP+ <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+ 1.1.1

dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose <=> dTDP-L-oleandrose not assigned

dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose <=> maltol + dTDP + H+ not assigned

dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose 5.1.3

S-adenosyl-L-methionine + dTDP-4-amino-2,4-dideoxy-beta-L-xylose <=> S-adenosyl-L-homocysteine + dTDP-4-methylamino-2,4-dideoxy-beta-L-xylose 2.1.1

dTDP-6-deoxy-beta-L-talose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+)
1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]


dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + H2O + oxidized_ferredoxin 4.2.1.164 dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase

dTDP-6-deoxy-beta-L-talose <=> dTDP-L-rhamnose 5.1.3.25 dTDP-L-rhamnose 4-epimerase

Visualization of the pathway